![]() Besides, this difference even exists in the studies conducted in a same country. The results of current study showed that the incidence of adverse reactions in blood donation can be very different from one country to another. Table 1 shows more details about all studies included in the systematic review. Moreover, 2.2% of the reactions were local and 2.8% were systemic. In Nigeria, as an African country, a study was conducted in 2017 on 459 blood donations, 5% of which caused adverse reactions. In this study, women and first donors made up 2.9% and 31.8% of all donors, respectively. ![]() Their latest study was conducted in 2017 on 1095 blood donations, the results of which showed that 10.2% of the total blood donations caused adverse reactions including 8.7% of local and 1.5% of systemic reactions. In Asia, India was the country with the most researches done related to adverse reactions in blood donation. In this study, women and first donors made up 47.8% and 82% of all donors, respectively. ![]() The study, which was done in 2012 on 928,411 donations, revealed that adverse reactions had occurred in 0.7% of all blood donations. In Europe, one of the most recent studies on the incidence of adverse reactions in blood donation was conducted in Germany. In this study, the proportion of women among donors was 46%. In the latest study in the United States of America, which was published in 2016, 30,868 blood donations were investigated, of which 0.34% had caused systemic reactions in blood donors. The incidence of adverse reactions in blood donation were explored continent by continent. In this study, a systematic review has been done on the incidence of adverse reactions in blood donation in different countries around the world and the incidence, as well as participation rate of women and first donors have been extracted. Īlthough the incidence of adverse reactions in blood donation is related to many factors, the sexual distribution of donors, as well as donation type (First, Regular) and race are the most affecting factors. Local reactions include hematoma, hemorrhage, bruising, and associated inflammation, while systemic reactions associated with dizziness, hyperventilation, pallor, bruising, and similar sings. Various adverse reactions may occur post blood donation, all of which are divided into two categories of local and systemic reactions. Therefore, eliminating or reducing these factors by means of prevention, can help to achieve this goal. This would be an obstacle against providing healthy and sufficient blood. Īlthough blood donation is a very low risk procedure, the incidence of some adverse reactions is inevitable which is the most important factor in reducing the donor’s desire to donate again. About 30% of all people have had a need to receive blood or its products during their life. This suggests that many factors can cause adverse reactions in blood donation, and that a wide range of them investigated in one study, most of which were systemic.īlood transfusion is known as a key component in every healthcare system which saves millions lives around the world each year. The difference did even existed in studies conducted in the same country and the same year. ![]() The incidence of adverse reactions in blood donation differ across the countries which might be related to the donors’ characteristics. Most reactions were systemic, and ranged from 0.08 to 13 percent in different countries. The results of the study showed that the reactions caused by blood donation are very different. After screening the remaining 4,537 documents, 97 one were reviewed for quality assessment, of which 30 with the appropriate quality were selected for the review process. In the initial search, 7054 documents were found, of which 2517 duplicates were excluded. This research was conducted through searching databases such as PubMed, Web of Science, Scopus, EmBase, Ovid, as well as the specialized journal of TRANSFUSION without any time limit by using the keywords including “Adverse Event”, “Adverse Effect”, “Adverse Reaction”, “Complication”, “Side Effect”, “Vasovagal Reaction”, “Local Reaction”, “General Reaction”, “Allergic Reaction”, “Blood Donor”, and “Blood Donation”. The present study is designed to investigate the incidence of adverse reactions in blood donation around the world. There are a lot of reports related to adverse reactions post blood donation.
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